PRECLINICAL CANCER OF THE
Spread of cancer through the lymphatic vessels is usually a precursor to secondary distant tumor formation. Identifying and characterizing this spreading tumor tissue is key to understanding the metastasis process. In cases involving darkly absorbing melanoma cells, MSOT has been utilized to image the spreading of incredibly small numbers of cells within the lymphatic network. Furthermore, molecular imaging strategies have been employed with MSOT to identify spreading cells and characterize the tumor microenvironment.