CLINICAL ISCHEMIA OF THE
Methods for imaging vascular structures include ultrasound (US), magnetic resonance (MRI), and X-ray computed tomography (XCT). US is non-invasive but suffers from an inherent lack of sensitivity and resolution. MRI and XCT provide high resolution but require injection of contrast agents. In early clinical trials, MSOT has demonstrated the potential to provide high-resolution imaging of vascular morphology and function without exogenous contrast, at different scales for superficial microvasculature as well as deeper-lying vessels.