Participate in an imaging revolution.

iThera Medical offers the next generation in molecular imaging. 
Introducing MSOT - Multispectral Optoacoustic Tomography.

With its unique ability to accurately visualize and quantify tissue molecules, nanoparticles, biomarkers and optical agents, in vivo and in real time, through several centimeters of tissue, MSOT stands at the forefront of the next era in biomedical imaging.

RSOM Small Animal Imaging

iThera Medical's high-resolution RSOM Explorer imaging systems facilitate a wide variety of imaging applications as well as extensive data analysis, and are yet easy to use. For more information: click here or play video to get a first-hand impression of the RSOM experiment procedure for small animal studies.

MSOT Clinical Translation

Based on the real-time multispectral imaging technology proven in iThera Medical’s MSOT inSight / inVision small animal imaging systems, a handheld MSOT imaging system for translational and clinical research use, the MSOT Acuity, is now available (not yet approved as a medical device by FDA or CE).

For more information: click here or play video.

MSOT Small Animal Imaging

iThera Medical offers a range of small animal scanners with varying hardware and software configurations. All systems enable whole-body deep-tissue imaging in real time.

For more information: click here.

Hybrid OA / US Technology

iThera Medical recently launched an integrated OPtoacoustic / UltraSound (OPUS) imaging technology. The MSOT inVision 512-echo is the world's first hybrid tomographic OPUS imaging system, providing unparalelled and user-independent image quality, in real time, throughout the entire animal cross-section.

For more information: click here.

Application Highlight: DCE-MSOT

MSOT has the capability to capture fast processes in vivo with high spatiotemporal resolution. Per-pixel analysis allows fitting of a pharmacokinetic model and calculation of parametric maps. Related applications include perfusion and probe targeting / clearance studies: see poster

  • MoBi 2018
    November 15-16, 2018
    Goettingen, Germany
  • RSNA 2018
    November 25-30, 2018
    Chicago, USA
  • Zhang H et al.,
    Monitoring the Opening and Recovery of the Blood-Brain Barrier with Noninvasive Molecular Imaging by Biodegradable Ultrasmall Cu2-xSe Nanoparticles,
    Nano Lett. 2018 Jul 18. DOI: 10.1021/acs.nanolett.8b01818.
  • Ma T et al.,
    "Smart" Nanoprobes for Visualization of Tumor Microenvironments,
    Adv Healthc Mater. 2018 Jul 12:e1800391. DOI: 10.1002/adhm.201800391.
  • Masthoff M et al.,
    Multispectral optoacoustic tomography of systemic sclerosis,
    J Biophotonics. 2018 Jul 4:e201800155. DOI: 10.1002/jbio.201800155.
  • Comenge J et al.,
    Multimodal cell tracking from systemic administration to tumour growth by combining gold nanorods and reporter genes,
    Elife. 2018 Jun 27;7. DOI: 10.7554/eLife.33140.
  • Abeyakoon O et al.,
    Optoacoustic Imaging Detects Hormone-Related Physiological Changes of Breast Parenchyma,
    Ultraschall Med. 2018 Jun 7. DOI: 10.1055/a-0628-6248.
  • Yücel YH et al.,
    Active Lymphatic Drainage From the Eye Measured by Noninvasive Photoacoustic Imaging of Near-Infrared Nanoparticles,
    Invest Ophthalmol Vis Sci. 2018 Jun 1;59(7):2699-2707. DOI: 10.1167/iovs.17-22850.
  • Han Z et al.,
    An Innovation for Treating Orthotopic Pancreatic Cancer by Preoperative Screening and Imaging-Guided Surgery,
    Mol Imaging Biol. 2018 Jun 1. DOI: 10.1007/s11307-018-1209-8.
  • O'Kelly D et al.,
    Tomographic breathing detection: a method to noninvasively assess in situ respiratory dynamics,
    J Biomed Opt. 2018 May;23(5):1-6. DOI: 10.1117/1.JBO.23.5.056011.
  • Sun J et al.,
    Ultrasmall endogenous biopolymer nanoparticles for magnetic resonance/photoacoustic dual-modal imaging-guided photothermal therapy,
    Nanoscale. 2018 May 29. DOI: 10.1039/c8nr01215f.
  • Sigmund F et al.,
    Bacterial encapsulins as orthogonal compartments for mammalian cell engineering,
    Nat Commun. 2018 May 18;9(1):1990. DOI: 10.1038/s41467-018-04227-3.
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