Listening to molecules

Optoacoustic imaging. The next-generation in molecular imaging.

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Introduction to optoacoustic imaging

How can optoacoustic imaging benefit you?

Due to its favorable characteristics in terms of spatiotemporal resolution, penetration depth, sensitivity and specificity, OAI can be used for a multitude of applications, for both preclinical and clinical research:

MSOT and RSOM in preclinical research

Preclinical research

In the past 5-10 years, OAI has become an established imaging modality for in vivo preclinical research. Based on its unique ability to differentiate endogenous chromophores and exogenous probes, a wide variety of applications have been successfully explored.

Tumor characterization Functional brain imaging Assessment of organ function Nanoparticle tracking Other preclinical applications

MSOT and RSOM in clinical research

Clinical research

Following the success of OAI in preclinical research, the technology has already transitioned into clinical use. Main areas of interest for clinical trials have so far been oncology, cardiology and inflammation. The future is bright for OAI in clinical diagnosis!

Crohn’s disease imaging Breast cancer imaging Melanoma detection Other clinical applications

iThera Medical – leading the field of optoacoustic imaging

Macroscopic imaging

iThera Medical’s MSOT inVision series is the only optoacoustic imaging system with real-time whole-body imaging capability for small animals. Multispectral optoacoustic tomography (MSOT) introduces a new standard for the exploration of biological processes and the kinetics of pharmacological substances.

At the same time, iThera Medical is the undisputed leader in translating OAI into the clinic. A significant number of clinical trials has been successfully completed using the MSOT Acuity, ranging from melanoma to breast cancer, from Crohn’s disease to systemic sclerosis.

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Mesoscopic imaging

iThera Medical is the only company offering OAI systems in the mesoscopic regime – achieving 2-3mm depth penetration at a resolution of down to 20µm.

Raster-scanning optoacoustic mesoscopy (RSOM) has so far been explored in a variety of tumor-associated preclinical studies, using the RSOM Explorer P50 to look at angiogenesis and changes in tumor vasculature under treatment. For clinical imaging, the RSOM Explorer C50 has been used for clinical trials in skin cancer and a wide range of skin diseases associated with inflammation.

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Contact us

Don’t hesitate to contact us if you have any questions about our technology, applications or products.

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