Participate in an imaging revolution.

iThera Medical offers the next generation in molecular imaging. 
Introducing MSOT - Multispectral Optoacoustic Tomography.

With its unique ability to accurately visualize and quantify tissue molecules, nanoparticles, biomarkers and optical agents, in vivo and in real time, through several centimeters of tissue, MSOT stands at the forefront of the next era in biomedical imaging.

MSOT Clinical Translation

Based on the real-time multispectral imaging technology proven in iThera Medical’s MSOT inSight / inVision small animal imaging systems, an MSOT imaging system for clinical use, the MSOT Acuity, is now available.

For more information: click here or play video.

MSOT Small Animal Imaging

iThera Medical offers a range of small animal scanners with varying hardware and software configurations. All systems enable whole-body deep-tissue imaging in real time.

For more information: click here.

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MSOT inVision Experiment Workflow

iThera Medical's MSOT imaging systems facilitate a wide variety of imaging applications as well as extensive data analysis, and are yet easy to use. To get a first-hand impression of the MSOT experiment procedure for small animal studies, follow this link: play video

Launch of Hybrid OA / US Technology

iThera Medical proudly announces the launch of its integrated optoacoustic / ultrasound (OPUS) imaging technology. The MSOT inVision 512-echo is the world's first hybrid tomographic OPUS imaging system, providing unparalelled and user-independent image quality, in real time, throughout the entire animal cross-section.

For more information: click here.

Application Highlight: DCE-MSOT

MSOT has the capability to capture fast processes in vivo with high spatiotemporal resolution. Per-pixel analysis allows fitting of a pharmacokinetic model and calculation of parametric maps. Related applications include perfusion and probe targeting / clearance studies: see poster

xPLORE Probes

iThera Medical markets a proprietary line of probes optimized for the use with MSOT. The initial portfolio of three xPLORE© probes consists of two targeted reagents for the use in disease models related to cancer and inflammation as well as one blood pool agent with long circulation time.

For more information: click here.

  • Lorne Cancer Conference
    February 11-13, 2016
    Mantra Lorne, Australia
  • ECR 2016
    Booth: Hall X5, #22
    March 2-6, 2016
    Vienna, Austria
  • EMIM 2016
    Booth #19
    March 8-10, 2016
    Utrecht, The Netherlands
  • AACR 2016
    Booth #230
    April 16-20, 2016
    New Orleans, USA
  • SNMMI 2016
    Booth #316
    June 11-15, 2016
    San Diego, USA
  • WMIC 2016
    September 7-10, 2016
    New York, USA
  • RSNA 2016
    Booth: Hall B, #6909
    November 27 - December 2, 2016
    Chicago, USA
  • SJ Ford et al.,
    Structural and Functional Analysis of Intact Hair Follicles and Pilosebaceous Units by Volumetric Multispectral Optoacoustic Tomography,
    J Invest Dermatol. 2015 Dec 30. DOI: 10.1016/j.jid.2015.09.001.
  • Ingo Stoffels et al.,
    Metastatic status of sentinel lymph nodes in melanoma determined noninvasively with multispectral optoacoustic imaging,
    Sci. Transl. Med. 09 Dec 2015. DOI: 10.1126/scitranslmed.aad1278.
  • Wenyuan Yin et al.,
    Tumor specific liposomes improve detection of pancreatic adenocarcinoma in vivo using OAT,
    J Nanobiotechnol (2015) 13:90. DOI 10.1186/s12951-015-0139-8.
  • Thomas Felix Fehm et al.,
    Volumetric optoacoustic imaging feedback during endovenous laser therapy – an ex-vivo investigation,
    J. Biophotonics 1–8 (2015). DOI 10.1002/jbio.201500210.
  • Xie B et al.,
    Necrosis avid near infrared fluorescent cyanines for imaging cell death and their use to monitor therapeutic efficacy in mouse tumor models,
    Oncotarget. 2015 Oct 12. DOI: 10.18632/oncotarget.5498.
  • Merčep E. et al.,
    Whole-body live mouse imaging by hybrid reflection-mode ultrasound and optoacoustic tomography,
    Opt. Lett. 40, 4643-4646 (2015). DOI: 10.1364/OL.40.004643.
  • Qiao An et al.,
    Multifunctional Magnetic Gd 3+ -Based Coordination Polymer Nanoparticles: Combination of Magnetic Resonance and Multispectral Optoacoustic Detections for Tumor-Targeted Imaging in vivo,
    Small. 2015 Sep 14. DPO: 10.1002/smll.201501491.
  • Anil Khanal et al.,
    Tumor targeted mesoporous silica-coated gold nanorods facilitate detection of pancreatic tumors using Multispectral optoacoustic tomography,
    Nano Res. December 2015, Volume 8, Issue 12, pp 3864-3877. DOI 10.1007/s12274-015-0886-8.
  • Scarfe L et al.,
    Measures of kidney function by minimally invasive techniques correlate with histological glomerular damage in SCID mice with adriamycin-induced nephropathy,
    Sci. Rep. 5, 13601 (2015). DOI:10.1038/srep13601.
  • Charles W Kimbrough et al.,
    Targeting Acidity in Pancreatic Adenocarcinoma: Multispectral Optoacoustic Tomography Detects pH-low Insertion Peptide Probes in vivo,
    Clin Cancer Res. 2015 Jun 29. PII: clincanres.0314.2015.
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