Participate in an imaging revolution.

iThera Medical offers the next generation in molecular imaging. 
Introducing MSOT - Multispectral Optoacoustic Tomography.

With its unique ability to accurately visualize and quantify tissue molecules, nanoparticles, biomarkers and optical agents, in vivo and in real time, through several centimeters of tissue, MSOT stands at the forefront of the next era in biomedical imaging.

MSOT Clinical Translation

Based on the real-time multispectral imaging technology proven in iThera Medical’s MSOT inSight / inVision small animal imaging systems, a handheld MSOT imaging system for translational and clinical research use, the MSOT Acuity, is now available (not yet approved as a medical device by FDA or CE).

For more information: click here or play video.

MSOT Small Animal Imaging

iThera Medical offers a range of small animal scanners with varying hardware and software configurations. All systems enable whole-body deep-tissue imaging in real time.

For more information: click here.

Hybrid OA / US Technology

iThera Medical recently launched an integrated OPtoacoustic / UltraSound (OPUS) imaging technology. The MSOT inVision 512-echo is the world's first hybrid tomographic OPUS imaging system, providing unparalelled and user-independent image quality, in real time, throughout the entire animal cross-section.

For more information: click here.

Application Highlight: DCE-MSOT

MSOT has the capability to capture fast processes in vivo with high spatiotemporal resolution. Per-pixel analysis allows fitting of a pharmacokinetic model and calculation of parametric maps. Related applications include perfusion and probe targeting / clearance studies: see poster

xPLORE Probes

iThera Medical markets a proprietary line of probes optimized for the use with MSOT. The initial portfolio of three xPLORE© probes consists of two targeted reagents for the use in disease models related to cancer and inflammation as well as one blood pool agent with long circulation time.

For more information: click here.

  • WMIC 2017
    September 13-16, 2017
    Philadelphia, USA
  • RSNA 2017
    Booth #1805
    November 26 - December 1, 2017
    Chicago, USA
  • Berninger MT et al.,
    Detection of intramyocardially injected DiR-labeled mesenchymal stem cells by optical and optoacoustic tomography,
    Photoacoustics. 2017 Jun; 6: 37–47. DOI: 10.1016/j.pacs.2017.04.002
  • Jiang X et al.,
    Ultra-Small Magnetic CuFeSe2 Ternary Nanocrystals for Multimodal Imaging Guided Photothermal Therapy of Cancer,
    ACS Nano. 2017 May 19. DOI: 10.1021/acsnano.7b01032.
  • Bao S et al.,
    Gold nanocages with dual modality for image-guided therapeutics,
    Nanoscale. 2017 May 19. DOI: 10.1039/c7nr01350g.
  • Mercep E et al.,
    Combined Pulse-Echo Ultrasound and Multispectral Optoacoustic Tomography with a Multi-Segment Detector Array,
    IEEE Trans Med Imaging. 2017 May 18. DOI: 10.1109/TMI.2017.2706200.
  • Ni Y et al.,
    Push-pull type meso-ester substituted BODIPY near-infrared dyes as contrast agents for photoacoustic imaging,
    Org Biomol Chem. 2017 May 17. DOI: 10.1039/c7ob00965h.
  • Aguirre J et al.,
    Precision assessment of label-free psoriasis biomarkers with ultra-broadband optoacoustic mesoscopy,
    Nat. Biomed. Eng. 1, 0068 (2017). DOI:10.1038/s41551-017-0068.
  • Lin S et al.,
    Optically and acoustically triggerable sub-micron phase-change contrast agents for enhanced photoacoustic and ultrasound imaging,
    Photoacoustics. 2017 Apr 11;6:26-36. DOI: 10.1016/j.pacs.2017.04.001.
  • Yang Hu et al.,
    Multifunctional hetero-nanostructures of hydroxyl-rich polycation wrapped cellulose-gold hybrids for combined cancer therapy
    J Control Release. 2017 Apr 3. DOI: 10.1016/j.jconrel.2017.04.001.
  • Knieling F et al.,
    Multispectral Optoacoustic Tomography for Assessment of Crohn’s Disease Activity,
    N Engl J Med. 2017 Mar 30;376(13):1294-6. DOI: 10.1056/NEJMc1612455.
  • Vipul Gujrati et al.,
    Molecular imaging probes for multi-spectral optoacoustic tomography,
    Chem. Commun., 2017,53, 4653-4672. DOI: 10.1039/C6CC09421J.
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