Participate in an imaging revolution.

iThera Medical offers the next generation in molecular imaging. 
Introducing MSOT - Multispectral Optoacoustic Tomography.

With its unique ability to accurately visualize and quantify tissue molecules, nanoparticles, biomarkers and optical agents, in vivo and in real time, through several centimeters of tissue, MSOT stands at the forefront of the next era in biomedical imaging.

MSOT Clinical Translation

Based on the real-time multispectral imaging technology proven in iThera Medical’s MSOT inSight / inVision small animal imaging systems, a handheld MSOT imaging system for translational and clinical research use, the MSOT Acuity, is now available (not yet approved as a medical device by FDA or CE).

For more information: click here or play video.

MSOT Small Animal Imaging

iThera Medical offers a range of small animal scanners with varying hardware and software configurations. All systems enable whole-body deep-tissue imaging in real time.

For more information: click here.

Hybrid OA / US Technology

iThera Medical recently launched an integrated OPtoacoustic / UltraSound (OPUS) imaging technology. The MSOT inVision 512-echo is the world's first hybrid tomographic OPUS imaging system, providing unparalelled and user-independent image quality, in real time, throughout the entire animal cross-section.

For more information: click here.

Application Highlight: DCE-MSOT

MSOT has the capability to capture fast processes in vivo with high spatiotemporal resolution. Per-pixel analysis allows fitting of a pharmacokinetic model and calculation of parametric maps. Related applications include perfusion and probe targeting / clearance studies: see poster

xPLORE Probes

iThera Medical markets a proprietary line of probes optimized for the use with MSOT. The initial portfolio of three xPLORE© probes consists of two targeted reagents for the use in disease models related to cancer and inflammation as well as one blood pool agent with long circulation time.

For more information: click here.

  • AACR 2017
    Booth #642
    April 1-5, 2017
    Washington, D.C., USA
  • EMIM 2017
    Booth #13
    April 5-7, 2017
    Cologne, Germany
  • MPIC 2017
    May 14-16, 2017
    Nashville, USA
  • SNMMI 2017
    Booth #911
    June 10-14, 2017
    Denver, USA
  • WMIC 2017
    September 13-16, 2017
    Philadelphia, USA
  • RSNA 2017
    Booth #1805
    November 26 - December 1, 2017
    Chicago, USA
  • Knieling F et al.,
    Multispectral Optoacoustic Tomography for Assessment of Crohn’s Disease Activity,
    N Engl J Med. 2017 Mar 30;376(13):1294-6. DOI: 10.1056/NEJMc1612455.
    Link
  • Zhang S et al.,
    Terrylenediimide-Based Intrinsic Theranostic Nanomedicines with High Photothermal Conversion Efficiency for Photoacoustic Imaging-Guided Cancer Therapy,
    ACS Nano. 2017 Mar 21. DOI: 10.1021/acsnano.6b08720.
    Link
  • Yuping Yan et al.,
    Heteropoly blue doped polymer nanoparticles: an efficient theranostic agent for targeted photoacoustic imaging and near-infrared photothermal therapy in vivo,
    J. Mater. Chem. B, 2017,5, 382-387. DOI: 10.1039/C6TB02652D.
    Link
  • Liu T et al.,
    A Poly(L-glutamic acid)-Combretastatin A4 Conjugate for Solid Tumor Therapy: Markedly Improved Therapeutic Efficiency through Its Low Tissue Penetration in Solid Tumor,
    Acta Biomater. 2017 Feb 3. DOI: 10.1016/j.actbio.2017.02.001.
    Link
  • Joseph J et al.,
    Evaluation of precision in optoacoustic tomography for preclinical imaging in living subjects,
    J Nucl Med. 2017 Jan 26. DOI: 10.2967/jnumed.116.182311.
    Link
  • Sun Y et al.,
    Multifunctional polycationic photosensitizer conjugates with rich hydroxyl groups for versatile water-soluble photodynamic therapy nanoplatforms,
    Biomaterials. 2016 Dec 1;117:77-91. DOI: 10.1016/j.biomaterials.2016.11.055.
    Link
  • Kannadorai RK et al.,
    Noninvasive in vivo multispectral optoacoustic imaging of apoptosis in triple negative breast cancer using indocyanine green conjugated phosphatidylserine monoclonal antibody,
    J Biomed Opt. 2016 Dec 1;21(12):126002. DOI: 10.1117/1.JBO.21.12.126002.
    Link
  • Cheng X et al.,
    Light-Triggered Assembly of Gold Nanoparticles for Photothermal Therapy and Photoacoustic Imaging of Tumors In Vivo,
    Adv Mater. 2016 Dec 6. DOI: 10.1002/adma.201604894.
    Link
  • Bhutiani N et al.,
    Non-invasive Imaging of Colitis using Multispectral Optoacoustic Tomography,
    J Nucl Med. 2016 Dec 1. PII: jnumed.116.184705.
    Link
  • Shang W et al.,
    Core-Shell Gold Nanorod@Metal-Organic Framework Nanoprobes for Multimodality Diagnosis of Glioma,
    Adv Mater. 2016 Nov 18. DOI: 10.1002/adma.201604381.
    Link
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