Participate in an imaging revolution.

iThera Medical offers the next generation in molecular imaging. 
Introducing MSOT - Multispectral Optoacoustic Tomography.

With its unique ability to accurately visualize and quantify tissue molecules, nanoparticles, biomarkers and optical agents, in vivo and in real time, through several centimeters of tissue, MSOT stands at the forefront of the next era in biomedical imaging.

MSOT Clinical Translation

Based on the real-time multispectral imaging technology proven in iThera Medical’s MSOT inSight / inVision small animal imaging systems, a handheld MSOT imaging system for translational and clinical research use, the MSOT Acuity, is now available (not yet approved as a medical device by FDA or CE).

For more information: click here or play video.

MSOT Small Animal Imaging

iThera Medical offers a range of small animal scanners with varying hardware and software configurations. All systems enable whole-body deep-tissue imaging in real time.

For more information: click here.

Hybrid OA / US Technology

iThera Medical recently launched an integrated OPtoacoustic / UltraSound (OPUS) imaging technology. The MSOT inVision 512-echo is the world's first hybrid tomographic OPUS imaging system, providing unparalelled and user-independent image quality, in real time, throughout the entire animal cross-section.

For more information: click here.

Application Highlight: DCE-MSOT

MSOT has the capability to capture fast processes in vivo with high spatiotemporal resolution. Per-pixel analysis allows fitting of a pharmacokinetic model and calculation of parametric maps. Related applications include perfusion and probe targeting / clearance studies: see poster

xPLORE Probes

iThera Medical markets a proprietary line of probes optimized for the use with MSOT. The initial portfolio of three xPLORE© probes consists of two targeted reagents for the use in disease models related to cancer and inflammation as well as one blood pool agent with long circulation time.

For more information: click here.

  • Roberts S et al.,
    Calcium Sensor for Photoacoustic Imaging,
    J Am Chem Soc. 2017 Sep 25.
    Link
  • Diot G et al.,
    Multi-Spectral Optoacoustic Tomography (MSOT) of human breast cancer,
    Clin Cancer Res. 2017 Sep 12.
    Link
  • Shah A et al.,
    Value of combining dynamic contrast enhanced ultrasound and optoacoustic tomography for hypoxia imaging,
    Photoacoustics. 2017 Sep 7;8:15-27.
    Link
  • Schwarz M et al.,
    Motion correction in optoacoustic mesoscopy
    ,
    Sci Rep. 2017 Sep 4;7(1):10386.
    Link
  • Landa FJO et al.,
    Volumetric Optoacoustic Temperature Mapping in Photothermal Therapy,
    Sci Rep. 2017 Aug 29;7(1):9695.
    Link
  • Mason RP,
    Oxygen breathing challenge- the simplest theranostic,
    Theranostics 2017; 7(16):3873-3875.
    Link
  • Ju Y et al.,
    Monodisperse Au-Fe2C Janus Nanoparticles: An Attractive Multifunctional Material for Triple-Modal Imaging-Guided Tumor Photothermal Therapy,
    ACS Nano. 2017 Sep 26;11(9):9239-9248.
    Link
  • Xiao W et al.,
    Normalizing Tumor Vessels To Increase the Enzyme-Induced Retention and Targeting of Gold Nanoparticle for Breast Cancer Imaging and Treatment,
    Mol Pharm. 2017 Sep 5.
    Link
  • Xie B et al.,
    Optoacoustic detection of early therapy-induced tumor cell death using a targeted imaging agent,
    Clin Cancer Res. 2017 Aug 18.
    Link
  • Shah A et al.,
    Detecting human melanoma cell re-differentiation following BRAF or heat shock protein 90 inhibition using photoacoustic and magnetic resonance imaging,
    Sci Rep. 2017 Aug 15;7(1):8215.
    Link
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